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Truvada is the closest thing there is to an HIV vaccine. When taken daily, the small blue pill is up to 99 percent effective at preventing HIV. This kind of preventative approach, is technically called PrEP (pre-exposure prophylaxis). It was approved by the FDA in 2012 and has relatively minor side effects. For that reason, tens of thousands of people are now on the drug, says Huffpost. The drug has become the cornerstone of many cities’ campaigns against HIV/AIDS. However, accessing and affording Truvada isn’t as easy as it should be. This is especially true for patients living outside of urban areas. Out of pocket, Truvada costs between $8,000 and $14,000 a year.