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Preventing skin cancer obviously includes a serious SPF routine. We know this. But staying out of the sun isn't the only thing that impacts your risk of skin cancer — your diet and even certain medications have been linked to an increased risk. Now, a new study suggests that taking aspirin may significantly up the risk of melanoma in men. Doctors recommend a daily dose of aspirin to certain patients for two major reasons. First, it's long been lauded for its cardio-protective effects, according to the Mayo Clinic.