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A new study challenges the commonly held belief that flu epidemics originate in large cities. In fact, the four U.S. cities that “seeded” the 2009 flu epidemic are home to between 100,000 to 600,000 people each. Those cities were Grenada, Mississippi; Albany, Georgia; Stockton, California; and Omaha, Nebraska. Science Magazine reports three-quarters of all U.S. cases had its origins in one of these cities. The ‘Hollywood’ notion of a highly infectious pandemic starting in a major city is not the way things happen in reality. Stephen Kissler, Study Author University of Cambridge